Kolbot By is Vice President, Technical Operations and Chemical Development at Rain Therapeutics. He has over 25 years of experience in synthetic organic chemistry, solid-state chemistry, development and manufacturing of small molecules, late-stage development and validation, QbD-enabling CMC document preparation, and CMO management.
Prior to joining Rain he was VP of Chemical Development at Principia Biopharma, where he developed API manufacturing, invented and wrote patent applications for novel forms, supported phase 1 studies, and built a department of scientists to oversee all drug substance related manufacturing. Before Principia he spent time in senior drug development roles at Corvus Pharmaceuticals, Onyx Pharmaceuticals and ARYx Therapeutics. Prior to working in the biopharma industry, he was an instructor at the University of California, Davis.
Kolbot graduated with a Bachelor of Science in Chemistry from the University of California, Santa Barbara and received a Ph.D. in Synthetic Organic Chemistry from the University of California, Davis.